The Truth About Sickle Cell Disease

In 1910, a Chicago physician, James B. Herrick, discove reddish a new illness, called reaping hook carrell. He had written a communicate about a unhurried of his from the West Indies that had an anemia characterized by unusual red cells that were sickle shaped. As years went on, the study led to the locating of a new sickle cell, hemoglobin (HbS). Researchers discovered that Hemoglobin S had a bring low solubility than blueprint hemoglobin and predicted that the low oxygen of the deoxygenated red cells changed the structure of the hemoglobin.
What is sickle cell disease? Sickle cell disease, also called sickle cell anemia is a disease patrimonial through families in which red smear cells be an antidromic crescent shape. This disease is common among people whose ancestors get along from Africa, the Middle East, the Mediterranean basin, and India. In the U.S., it has the greatest affect on African Americans. Sickle cell anemia is caused by an abnormal type of hemoglobin called hemoglobin S (HbS). Hemoglobin is a protein inside red blood cells that carries oxygen. However, Hemoglobin S carries little oxygen to the bodys tissues. It also alters the shape of the blood cells and can break into pieces that can block the blood flow. traffic pattern and sickle hemoglobin differs in many ways.



average hemoglobin is found in disc-shaped red blood cells that are soft, which allows them to easy flow through small blood vessels. Sickle hemoglobin is hard and often gets stuck in small blood vessels and scratch the flow of blood. Another difference is sickle cells do not live as long as normal cells. Normal cells can survive for about 120 days, while sickle cells can survive for about 60 days or less. As a result, a sickle cell patient has fewer red blood cells and less hemoglobin than normal red blood cells. Sickle cell anemia is inherited as an autosomal

recessive trait, meaning that, in allege to pass the disease, both parents must have the hemoglobin S gene. Inheriting the hemoglobin S gene from only one parent and a...If you want to get a full essay, range it on our website: Orderessay



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